Conclusions (Slide 15):

In treatment of acute VTE, tinzaparin given once daily at 175 IU/kg is effective and safe. This regimen offers significant cost-savings because of the opportunity for out-patient treatment or early hospital discharge of selected patients.

In prevention of VTE after hip or knee replacement, tinzaparin in a dose of approximately 75 IU/kg given once daily is superior to placebo and roughly equal to either warfarin or enoxaparin. Prophylaxis should be continued for at least 7-10 days after surgery.

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